NADH plays a central role in energy production in cells.
February 10, 2025
Hanja Niederhammer
NADH, the energy molecule of our cells, is considered an anti-aging miracle and is indispensable for vitality and mental performance. We explore the effects of NADH and show how it promotes the health of the body, mind, and psyche.
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NADH is a central component of our energy metabolism and supports each cell in its function. As the biologically active form of Vitamin B3 it converts nutrients into energy and protects cells from damage. At the same time, it promotes the nervous system and contributes to mental clarity and vitality.
With age, the NADH level naturally decreases, which can noticeably affect energy and well-being. By consciously managing one's health, this process can be positively influenced – in addition, NADH can be specifically used to help with certain health issues.
NADH reacts in the cell with oxygen to transfer electrons and support ATP production. As a coenzyme, it promotes NO production and strengthens the immune system. Additionally, NADH acts as an antioxidant and positively influences cell functions.
NADH is formed in the body by the intake of vitamin B3 (niacin), an essential nutrient found in many foods. The body converts Niacin into NAD+, which then transitions into NADH through various metabolic processes – the active form that provides us with energy.
Merely through diet, the NADH level often cannot be significantly increased. Therefore, many people resort to dietary supplements – they are supposed to offer a direct way to specifically increase the NADH content in the body and brain.
Tip:Regular exercise, adequate sleep, and avoiding excessive stress also promote energy metabolism and help keep NADH levels balanced. A healthy lifestyle is therefore the key to providing your cells with sufficient energy.
NADH supplements provide the body with the coenzyme NADH in a directly usable form.
NADH plays a central role in the mitochondria , the “power plants” of our cells, by supporting the production of ATP – the body's main energy source.
In addition, it acts as an electron donor in redox reactions, promoting cellular repair and activating antioxidant defense mechanisms. NADH supplements provide the body directly with the coenzyme, enabling efficient support of energy production and cellular functions.
In short: NADH supplements provide the body with the coenzyme NADH in a readily usable form, effectively supporting the cells' energy production. They strengthen the cells' energy centers, promote repair processes, and offer a protective boost against cellular damage – real power for the body.
NADH is an essential energy supplier that supports the body and psyche equally. For people with general fatigue and exhaustion, a balanced diet provides a solid basis for naturally promoting cell energy, but the reduced content in food is often not enough to fully develop the effect of NADH in the form of noticeable effects.
That's why many turn to nutritional supplements , to specifically enhance the effect and take advantage of the versatile benefits of this coenzyme. But how exactly does NADH affect general well-being? And why is it particularly popular with athletes and frequent travelers?
After long flights and several hours of time difference, the internal clock gets out of balance – NADH could be the solution.Jet lag can slow down the body and mind – stabilized NADH, as found in dietary supplements, could play a supportive role here.
In an experiment, it was shown: participants who took a 20 mg NADH tablet before the flight achieved measurably better results in cognitive tests after landing than the control group without NADH. The study suggests that this coenzyme could gently alleviate the memory and concentration deficits caused by jet lag.
NADH also seems to play an interesting role in the field of sports Studies suggest that regular intake of NADH could increase muscular energy and reduce lactate levels during training – a potential advantage for athletes who rely on endurance and prolonged performance under aerobic conditions.
A study also showed that NADH can support not only physical but also mental performance by Concentration and reaction time improved. These results suggest that NADH could be a potential companion for more power and focus – however, research in this area is still open for further insights.
Not much is known about the effect of NADH on hair yet, but there are hints that sound exciting.
It is said that NADH could support energy production in hair follicles and thus promote hair growth. At the same time, its antioxidant effect is said to protect hair cells from damage, which could lead to stronger and healthier hair.
Sounds promising - maybe the next step to revitalize hair from within. Definitely worth a try!
NADH could be the key to mental balance – a true power coenzyme that energizes not only the body but also the psyche.
Particularly noteworthy is its ability to promote mental clarity, concentration, and memory performance – exactly the aspects that often waver in stressful times or with advancing age. By optimizing the energy supply to brain cells and reducing oxidative stress, NADH shows its potential to support mental vitality in a gentle way.
Scientific studies have investigated the effects of NADH in various disease patterns and have provided initial evidence of a possible positive influence from taking NADH supplements.
However, the research is not yet complete – an exciting field that continues to promise new insights to fully understand the exact mechanisms of action.
The possible effect of NADH on Depression sheds a fascinating light on this essential coenzyme. A study suggests that NADH not only supports the energy supply of cells but also has the potential to alleviate depressive symptoms.
The study showed that targeted administration of NADH in a specific dosage significantly improved the subjects' ability to actively cope with stressful situations, suggesting that NADH could promote motivation and resilience.
NADH and its potential impact on neurodegenerative diseases such as Alzheimer's are increasingly being researched. In a study by Georgetown University, Alzheimer patients received 10 mg of NADH daily for six months.
The results showed that patients treated with NADH did not experience further deterioration of cognitive functions. At the same time, their language skills, spatial imagination, and ability to think abstractly improved. However, no significant differences were observed in attention or memory.
In parallel, the role of NAD+ - a precursor of NADH that is essential in the body for energy production and cell regeneration - is increasingly coming into the focus of science. A more recent study from 2021 shows that NAD+ regulates crucial processes that are key to the development and progression of Alzheimer's relevant sind.
Das wachsende Verständnis dieser molekularen Mechanismen verdeutlicht die Wirkung von NADH auf das Gehirn und eröffnet vielversprechende Ansätze für neue Therapien. Forscher sehen großes Potenzial darin, den NAD+-Stoffwechsel gezielt zu beeinflussen, um Symptome zu lindern und möglicherweise den Krankheitsverlauf positiv zu beeinflussen.
Eine Studie über die Anwendung von NADH bei Rosazea und Kontaktdermatitis liefert spannende Einblicke in die potenzielle Wirkung von NADH auf die Haut.
Die Ergebnisse zeigen, dass eine 1%ige NADH-Salbe Rötungen, Entzündungen und Papeln bei Rosazea und Kontaktdermatitis signifikant reduzieren kann – und das ganz ohne Nebenwirkungen.
Lesen Sie hier: Wie man Rosazea behandeln und heilen kann
Neben seiner beruhigenden Wirkung auf gereizte Haut wird NADH als starkes Antioxidant also appreciated for its protection against oxidative stress, which could contribute to improving skin texture and elasticity.
Although the effect of NADH on the skin in skincare products is still being researched, the findings so far suggest promising possibilities to support skin health and radiance.
As a silent supporter in the background, NADH promotes crucial processes such as gluconeogenesis - the formation of new glucose - and fatty acid oxidation, both of which are essential for a smooth energy metabolism.
But that's not all that's known about the effect of NADH on the liver: The coenzyme is said to protect the liver from daily stresses that can arise from alcohol, medication, or oxidative stress, and to contribute to cell regeneration.
These effects have been confirmed in studies conducted by Professor Birkmayer together with renowned universities worldwide, including the University of Graz and Cornell University in New York.
Even though science has not yet deciphered everything about this fascinating helper, there is much to suggest that NADH is a valuable partner for liver health.
It seems that more and more people are discovering the "energy boost" from NADH supplements to take their performance and concentration to the next level. However, as with any true insider tip, the right dosage makes the difference so that the positive effects work without unwanted side effects.
The onset of action of NADH varies from person to person. While some users experience a noticeable increase in their energy and mental clarity after just a few hours, it may take several days or even weeks for others before the effect kicks in.
This depends on factors such as individual bioavailability and metabolism. Generally, a significant improvement in physical and mental performance is observed, especially with continuous intake over a longer period.
In general, NADH is considered well-tolerated and poses no health risks for most people. However, there are no specific data on possible interactions with other drugs or supplements, so it is always advisable to consult a doctor before taking it.
Interestingly, nicotinic acid (Vitamin B3) is often confused with NADH - although both are related, they are not the same. Nicotinic acid is used in the body to synthesize NAD+, while NADH is the reduced form of NAD+.
Excessive intake of nicotinic acid can pose health risks, which is clearly emphasized by the German Federal Institute for Risk Assessment (BfR). It is therefore important to understand the differences between these two forms to avoid potential risks.
NADH, the reduced form of NAD+ (nicotinamide adenine dinucleotide), is an essential Coenzyme, which occurs in all living cells and plays a central role in energy metabolism. It acts as an electron transporter in cellular respiration, a process in which energy is produced in the form of ATP (adenosine triphosphate). By providing electrons for the electron transport chain in the mitochondria, NADH enables the efficient production of ATP, the main energy source of cells.
For all the non-biochemists among us: Just think of NADH as the 'energy courier' in your body. It ensures that the cells have enough power to perform their tasks - the 'energy supplier' for your cells, so to speak. In addition, NADH is crucial for cell repair and the regulation of cell functions - particularly valuable as we age, since the body's own production of NADH decreases over time.
NADH is a substance found in the body that plays a central role in energy metabolism. In the right dosage, it is therefore not harmful but can specifically support the body. Taking NADH in the form of dietary supplements can promote energy production in the cells, which can be particularly helpful in cases of fatigue or mental exhaustion. Of course, it is important to observe the dosage recommendations and, if necessary, consult a doctor or pharmacist to consider individual needs.
NAD+ (nicotinamide adenine dinucleotide) is an essential compound in our body that is involved in numerous processes of energy metabolism and cell repair. It acts as an electron acceptor in redox reactions, while NADH, its reduced form, donates electrons and thus drives energy production in the mitochondria.
The question is often asked whether NAD+ or NADH is 'better' – but the answer lies in their collaboration. NAD+ and NADH are two states of the same molecule that are constantly being converted into each other in the body to maintain cell function.
NAD+ is the key to activating many enzymes including sirtuins, which are important for cell aging and regeneration, while NADH is directly involved in energy production. Both are essential and their functions complement each other – they are not interchangeable, but work harmoniously for cell health.
After long flights and several hours of time difference, the internal clock becomes unbalanced - NADH could be the solution.
A reduced lactate level after taking NADH implies extended performance in endurance sports.
NADH can have an extremely positive effect on the psyche.
A study suggests that NADH has the potential to alleviate depressive symptoms.
A 1% NADH cream can significantly reduce redness, inflammation, and papules in rosacea and contact dermatitis.
NADH supports a strong and healthy liver.
For most healthy adults, experts recommend a daily amount of NADH of 5 to 10 mg.
